Incidence of Toxoplasmosis in Pregnant Women in Western

Autores/as

  • Ahmet Uysal MH, Seferihisar Necat Hepkon State Hospital, Obstetric &Gynecology, Izmir, TURKEY
  • Mete Cüce MH, Aegean Maternity and Teaching Hospital, Microbiology, Izmir, TURKEY
  • Cüneyt Taner MH, Aegean Maternity and Teaching Hospital, Obstetric &Gynecology, Izmir, TURKEY
  • Fatma Uysal MH Konak Maternity Hospital, Radiology, Izmir, TURKEY
  • Sabri Atalay MH Tepecik Teaching and Training Hospital, Infectious Disease, Izmir, TURKEY
  • Basak Göl MH Tepecik Teaching and Training Hospital, Infectious Disease, Izmir, TURKEY
  • Sükran Köse MH Tepecik Teaching and Training Hospital, Infectious Disease, Izmir, TURKEY

Palabras clave:

Pregnancy, Toxoplasmosis, congenital, Toxoplasma gondii

Resumen

PREVALENCE OF CONGENITAL TOXOPLASMOSIS AMONG A SERIES OF TURKISH WOMEN

Background: Toxoplasma gondii infection during pregnancy causes congenital malformations. Pregnant women should be screened for this infection since it is preventable and treatable. Aim: To study the seroprevalence of Toxoplasma gondii infection among pregnant women living in Izmir, Turkey. Material and Methods: A blood sample was obtained from 4651 women aged between 15 and 45 years, during their first trimester of pregnancy. IgM and IgG antibodies against Toxoplasma gondii were measured using an ELISA assay. Among women with both IgG and IgM antibodies positive, an IgG avidity test was performed, using a VIDAS kit.  Results: IgG antibodies were positive in 1871 (39.9%) participants. Of these, 48 (2.5%) also had positive IgM antibodies. In 41 of these 48 women, the IgG avidity test was performed and only one woman had a low avidity. This woman was treated with Spiramycin. Her offspring had an intrauterine growth retardation and oligohydramnios. A chorioretinitis was diagnosed in the offspring of other woman with both antibodies positive. Conclusions: In this series, the prevalence of congenital toxoplasmosis was low. However, women with positive antibodies against Toxoplasma Gondii should be further studied and followed during their pregnancy.  

PREVALENCIA DE TOXOPLASMOSIS CONGÉNITA EN UNA SERIE DE MUJERES EN TURQUÍA

Antecedentes: La infección por Toxoplasma gondii durante el embarazo causa malformaciones congénitas. Se debe efectuar serología para esta infección en mujeres embarazadas ya que es prevenible y tratable. Objetivo: Estudiar la seroprevalencia de infección por Toxoplasma gondii en mujeres embarazadas que viven en Izmir, Turquía. Material y métodos: Se obtuvo una muestra de sangre en 4651 mujeres cuyas edades fluctuaban entre 15 y 45, años, durante su primer trimestre de embarazo. Los anticuerpos IgM e IgG en contra de Toxoplasma Gondii se midieron por ELISA. En mujeres que tenían anticuerpos IgG e IgM positivos, un ensayo de avidez de IgG se efectuó utilizando el kit VIDAS. Resultados: Los anticuerpos IgG fueron positivos en 1871 participantes (39.9%). De estas, 48 (2.5%) también tenían anticuerpos IgM positivos. En  41 de estas 48 mujeres, se efectuó el test de avidez y sólo una tenía una baja avidez. Esta mujer se trató con espiramicina y su producto de concepción tuvo un retardo de crecimiento intrauterino y un oligohidroamnios. Una corioretinitis se diagnosticó en el producto de concepción de otra mujer con ambos anticuerpos positivos. Conclusiones: La seroprevalencia de toxoplasmosis congénita en esta serie de pacientes fue baja, sin embargo las mujeres con anticuerpos positivos deben ser tratadas y seguidas.

 

 

 

 


Biografía del autor/a

Ahmet Uysal, MH, Seferihisar Necat Hepkon State Hospital, Obstetric &Gynecology, Izmir, TURKEY

Dr. Ahmet Uysal Seferihisar Necat Hepkon State Hospital Chief Physician Seferihisar / ?ZM?R Tel: + 90 533 263 55 40 Email: drahmetuysal@hotmail.com

Mete Cüce, MH, Aegean Maternity and Teaching Hospital, Microbiology, Izmir, TURKEY

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Cüneyt Taner, MH, Aegean Maternity and Teaching Hospital, Obstetric &Gynecology, Izmir, TURKEY

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Fatma Uysal, MH Konak Maternity Hospital, Radiology, Izmir, TURKEY

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Sabri Atalay, MH Tepecik Teaching and Training Hospital, Infectious Disease, Izmir, TURKEY

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Basak Göl, MH Tepecik Teaching and Training Hospital, Infectious Disease, Izmir, TURKEY

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Sükran Köse, MH Tepecik Teaching and Training Hospital, Infectious Disease, Izmir, TURKEY

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Publicado

2013-04-05

Cómo citar

Uysal, A., Cüce, M., Taner, C., Uysal, F., Atalay, S., Göl, B., & Köse, S. (2013). Incidence of Toxoplasmosis in Pregnant Women in Western. Revista Médica De Chile, 141(4). Recuperado a partir de https://revistamedicadechile.cl/index.php/rmedica/article/view/2322

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Artículos de Investigación